Publications.

Scientific Articles.

SonoVue® vs. Sonazoid™ vs. Optison™: Which Bubble Is Best for Low-Intensity Sonoporation of Pancreatic Ductal Adenocarcinoma?

Pharmaceutics, 14(98), 2022

Ultrasound and Microbubbles Enhance Uptake of Doxorubicin in Murine Kidneys

Pharmaceutics, 13 (2038), 2021

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Acoustic Cluster Therapy (ACT®) enhances accumulation of polymeric micelles in the murine brain.

Journal of Controlled Release, 337, 2021

Graphical Abstract

Selecting the optimal parameters for sonoporation of pancreatic cancer in a pre-clinical model.

Cancer Biology and Therapy, 22 (3), 2021

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Low-intensity sonoporation-induced intracellular signalling of pancreatic cancer cells, fibroblasts and endothelial cells

Pharmaceutics, 12 (11), 2020

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Intracellular cytidine deaminase regulates gemcitabine metabolism in pancreatic cancer cell lines

Drug Metabolism and Disposition, 48 (3), 2020

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Theranostic attributes of ACT and its use for enhancing the effectiveness of liposomal doxorubicin treatment of human triple negative breast cancer in mice

Frontiers in pharmacology, 11 (75), 2020

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Ultrasound- and Microbubble-Assisted Gemcitabine Delivery to Pancreatic Cancer Cells

Pharmaceutics, 12 (2), 2020

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Sonoporation for augmenting chemotherapy of pancreatic ductal adenocarcinoma

Drug Delivery Systems, 2020

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Therapeutic dose response of acoustic cluster therapy in combination with irinotecan for the treatment of human colon cancer in mice

Frontiers in pharmacology, 10 (1299), 2020

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Intracellular signaling in key pathways is induced by treatment with ultrasound and microbubbles in a leukemia cell line, but not in healthy peripheral blood mononuclear cells

Pharmaceutics, 11 (7), 2019

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Measured acoustic intensities for clinical diagnostic ultrasound transducers and correlation with thermal index it stand out

Ultrasound in Obstetrics & Gynecology, 50 (2), 2017

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Sonoporation with Acoustic Cluster Therapy (ACT®) induces transient tumour volume reduction in a subcutaneous xenograft model of pancreatic ductal adenocarcinoma

Journal of Controlled Release, 245, (2017)

Books and book Chapters.

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Sonoporation to Enhance Drug Delivery in Metastatic Pancreatic Cancer.

Textbook of Pancreatic Cancer, (2021)

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Physical Principles of Medical Ultrasound

EFSUMB Course Book, 2nd Edition, (2019)

Conference Proceedings.

Acoustic Cluster Therapy enhances the efficacy of chemotherapeutic regimens in patient-derived xenograft mouse models for pancreatic ductal adenocarcinoma
Format : Poster

Moelcular Cancer Therapeutics, 18 (12), (2019)

Acoustic Cluster Therapy displays theranostic capability in enhancing the effectiveness of liposomal doxorubicin treatment of human triple negative breast cancer in mice
Format : Conference Proceeding

IEEE International Ultrasonics Symposium (2019)

Molecular mechanisms of sonoporation in pancreatic ductal adenocarcinoma (PDAC)
Format : Poster
Pancreatology S164 (2019)

Role of intracellular cytidine deaminase activity for gemcitabine metabolism in pancreatic cancer cell lines
Format : Poster

Pancreatology S157 (2019)

In vitro optimisation of sonoporation conditions in pancreatic cancer
Format : Poster
Pancreatology S151-152 (2019)

Sonoporation and gemcitabine delivery in pancreatic cancer cell lines
Format : Poster
Pancreatology S156 (2019)