Our Work.
Computer Aided Design.
Working with leading CAD programs we can help you design, evaluate, and improve your prototypes for various production methods such as 3D printing, CNC machining or moulding. We also produce animations, renderings, engineering drawing and more. Projects we have worked on include:
High-throughput cellular ultrasound exposure system - Design, development and testing of a computer controlled ultrasound chamber for treating adherent and non-adherent cells. Designs were 3D printed using a resin printer.
Anechoic hydrophone sheath - An experimental configuration process required acoustic fields to be measured in situ whilst in near contact with hard materials that could cause damage to the hydrophone. We designed a water-tight sheath that protected the hydrophone, and placed it at a precise sub-millimeter distance from the hard materials allowing safe and reproducible results.
Positioning and alignment clamps - Using 3D printing we designed, printed and tested custom alignment claps that allowed removal and re-positioning of complex geometry laboratory equipment within <0.5º and <500µm repeatability.
Simulations.
If you’ve ever needed to predict how your device will respond, if it can handle the stresses applied to it, or determine where the potential failure point is. Simulations are the service you need. We can model a wide range of physical behaviours to ensure you get the answers you need. Projects we have worked on include:
Ultrasonics Transducer modeling - We have modeled a range of 1D, 2D and 3D ultrasound arrays including acoustic transmission through complex materials to ensure the end output is as required and developed compensation methods to allow
Optically clear ultrasonic inspection windows - Devices designed in CAD can be modeled using static and dynamic stress to ensure that when used in e.g., high pressure environments any components, (e.g., glue, glass, plastic connectors) do not fail. The designs can then be optimised to have a pre-defined overhead to ensure longevity.
Microbubble oscillation prediction - We developed a MATLAB script that can model and predict the vibrational response of microbubbles to a ultrasound pulse of choice, near and far from boundaries across a range of sizes and physical properties.
Biotechnology.
Combining engineering and technology is essential to lead to medical products that improve society. We can help you decide on the best techniques for your application to answer the questions you need. We can also connect you to facilities world wide the the facilities and additional world-leading experience to help you solve your biotech question. Projects we have worked on include:
Three dimensional tumour organoid - Development of a 3D in vitro tumour model to allow evaluation of novel therapies in a significantly more realistic microenvironment.
Flow cytometry protocols - Establishment of SOPs for evaluation of drug uptake and intracellular responses post therapy evaluating the true impact of drugs and physical treatment to cells both in vitro and in vivo.
Drug loaded carriers for targeted deposition - Development of drug-loaded microparticles using multi-step emulsification techniques and evaluation of efficacy in vitro and in vivo using a range of theranostic modalities.
Scientific writing.
Our team has worked on over 25 peer reviewed publications in the field of engineering and biotechnology. Please see our Publications page for a list and examples of our writing.
